Electromechanical stresses produced in the plasma membranes of suspended cells by applied electric fields.

作者: Gary Bryant , Joe Wolfe

DOI: 10.1007/BF01869239

关键词: MembraneShell (structure)Materials scienceDielectrophoresisAnalytical chemistryField (physics)Composite materialDielectricSuspension (vehicle)Electric fieldPlasma

摘要: We analyze the electrical and mechanical stress in bounding membrane of a cell (or vesicle) suspension which is deformed by an external applied field. The treated as thin, elastic, initially spherical, dielectric shell analysis valid for frequencies less than reciprocal charging time (i.e. MHz), or constant fields. A complete analytic solution obtained, expressions are given relate deformation, surface tension transmembrane potential difference to show that tensions range lyse membranes induced at values field same order those reported plasma cells suspension.

参考文章(21)
U. Zimmermann, G. Pilwat, J. Vienken, Erythrocytes and lymphocytes as drug carrier systems: techniques for entrapment of drugs in living cells. Recent results in cancer research. ,vol. 75, pp. 252- 259 ,(1980) , 10.1007/978-3-642-81491-4_39
A.G. Petrov, M.D. Mitov, A.I. Derzhanski, Edge energy and pore stability in bilayer lipid membranes Advances in Liquid Crystal Research and Applications#R##N#Proceedings of the Third Liquid Crystal Conference of the Socialist Countries, Budapest, 27–31 August 1979. pp. 695- 737 ,(1981) , 10.1016/B978-0-08-026191-1.50004-9
Joe Wolfe, Michael F. Dowgert, Peter L. Steponkus, Mechanical study of the deformation and rupture of the plasma membranes of protoplasts during osmotic expansions The Journal of Membrane Biology. ,vol. 93, pp. 63- 74 ,(1986) , 10.1007/BF01871019
V. Dressler, K. Schwister, C.W.M. Haest, B. Deuticke, Dielectric breakdown of the erythrocyte membrane enhances transbilayer mobility of phospholipids Biochimica et Biophysica Acta (BBA) - Biomembranes. ,vol. 732, pp. 304- 307 ,(1983) , 10.1016/0005-2736(83)90216-X
Kenneth S. Cole, ELECTRIC IMPEDANCE OF SUSPENSIONS OF SPHERES. The Journal of General Physiology. ,vol. 12, pp. 29- 36 ,(1928) , 10.1085/JGP.12.1.29
L. D. Landau, J. S. Bell, J. B. Sykes, E. H. Dill, E. M. Lifshitz, Electrodynamics of continuous media ,(1960)
Joe Wolfe, Michael F. Dowgert, Peter L. Steponkus, Dynamics of membrane exchange of the plasma membrane and the lysis of isolated protoplasts during rapid expansions in area The Journal of Membrane Biology. ,vol. 86, pp. 127- 138 ,(1985) , 10.1007/BF01870779
R. Skalak, S. Weinbaum, E. A. Evans, Mechanics and Thermodynamics of Biomembranes ,(2017)
E. Sackmann, J. Engelhardt, K. Fricke, H. Gaub, On dynamic molecular and elastic properties of lipid bilayers and biological membranes Colloids and Surfaces. ,vol. 10, pp. 321- 335 ,(1984) , 10.1016/0166-6622(84)80033-5