Acute effects of different types of oil consumption on endothelial function, oxidative stress status and vascular inflammation in healthy volunteers.

作者: Dimitris Tousoulis , Nikolaos Papageorgiou , Charalambos Antoniades , Anastasios Giolis , George Bouras

DOI: 10.1017/S0007114509991346

关键词: Function (biology)BiologyInternal medicineCod liver oilBioavailabilityBiochemistryPlethysmographEndocrinologyEndotheliumInflammationHyperaemiaOxidative stress

摘要: Consumption of different types oil may have effects on cardiovascular risk. The exact role maize oil, cod liver soya and extra virgin olive endothelial function, oxidative stress inflammation is unknown. We evaluated the effect acute consumption these in healthy adults. Thirty-seven volunteers were randomised to receive an oral amount each type or water. Endothelial function was by gauge-strain plethysmography at baseline 1, 2 3 h after consumption. Oxidative status determined total lipid peroxides (PEROX), while inflammatory process estimated measuring soluble form vascular adhesion molecule 1. Serum levels two previous markers measured Reactive hyperaemia (RH) significantly decreased compared with controls (P < 0.05). However, induced a significant improvement RH 1 h, There no any endothelium-independent dilatation, PEROX serum levels. leads impaired slightly improve function. all oils did not affect systemic stress, suggesting that their be mediated free radicals bioavailability.

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