Guar gum effects on food intake, blood serum lipids and glucose levels of Wistar rats.

作者: A.C. Dario Frias , V.C. Sgarbieri

DOI: 10.1023/A:1008052216477

关键词: Diabetes mellitusFood scienceSmall intestineFood additiveBlood serumEndocrinologyInternal medicineCholesterolChemistryCyamopsisWeight gainGuar gum

摘要: The effects of guar gum derived from the endosperm Cyamopsis tetragonoloba (75% soluble fiber, 7.6% insoluble 2.16% crude protein, 0.78% total lipids, 0.54% ash and 9.55% moisture) on food intake, levels blood serum cholesterol, triacylglycerols, glucose LDL HDL-cholesterol were studied. indices protein absorption utilization also investigated. Diets containing 0%, 10% 20% (w/w) or cellulose powder (reference) fed to normal rats for 60 days. diets showed significantly (p ≤ 0.05) lower reduced intake body weight gain. Furthermore, a concomitant increase in with substantial elevation HDL/LDL cholesterol ratio noted. Guar decreased only during first month experiment, no changes found. caused small intestine length 25% retardation intestinal transit. results this research suggested that could potentially be effective treatment hypercholesterolemia obesity humans.

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