Evaluation of antifungal and anti-ochratoxigenic activities of Salvia officinalis, Lavandula dentata and Laurus nobilis essential oils and a major monoterpene constituent 1,8-cineole against Aspergillus carbonarius

摘要: Abstract This investigation is performed to evaluate the antifungal and anti-ochratoxigenic activities of Salvia officinalis, Lavandula dentata Laurus nobilis essential oils (EOs), their major constituent 1,8-cineole. The evaluation these was by two assays, contact assay with application different concentrations each tested EO as well 1,8-cineole (0, 0.1, 0.2, 0.3, 0.4 0.5%) in Czapek Yeast Agar medium (CYA) volatile one concentration equal 0.025% CYA. chemical composition EOs determined through gas chromatographic-mass spectrometry analysis antioxidant capacity assessed DPPH assay. Obtained results showed that L. exhibited better activity (IC50=0.35±0.05mg/mL) than S. officinalis (IC50=11.12±0.09mg/mL) dentate (IC50=14.03±0.16mg/mL) it possessed highest phenolic content (15.15 ± 1.64 mg gallic acid equivalent/g EO). Statistical analyses inhibited growth rate much more a percentage 47.82, 37.92 31.71%, respectively, reduced production OTA 88.87%. While, on higher minimum inhibitory (MIC) about 0.3 0.5%, respectively. MIC (0.5%) approximately double EOs. Hence, its powerful biological were assured synergism between component other existing ones.