Isolated intracranial Rosai-Dorfman disease mimicking meningioma.

摘要: Abstract Sinus histiocytosis with massive lymphadenopathy (SHML), also known as Rosai-Dorfman disease (RDD), is an idiopathic histiocytic proliferation affecting lymph nodes. It typically characterized by painless cervical lymphadenopathy, fever and weight loss. Although extranodal involvement has been reported in diverse sites, intracranial presentation, particularly the absence of nodal uncommon. To best our knowledge, 48 patients masses have previously. A 31-year-old man was admitted to clinic a 4-month history progressive headache. His medical unremarkable except for occasional fever. There were not any neurological deficit No (particularly bilateral cervical) sites revealed physical radiological examinations. Routine hematological biochemical studies normal mild leukocytosis elevated erythrocyte sedimentation rate. The patient underwent magnetic resonance imaging (MRI) testing that enhancing mass left temporal lobe. Preoperative diagnosis meningioma. frontotemporal craniotomy complete resection mass. Histopathology compatible RDD. Extranodal RDD rarely found intracranially. Prognosis benign especially disease. clinically radiologically difficult distinguish from meningioma, histological examination essential definitive diagnosis.