Is 2% chlorhexidine gluconate in 70% isopropyl alcohol more effective at preventing central venous catheter–related infections than routinely used chlorhexidine gluconate solutions: A pilot multicenter randomized trial (ISRCTN2657745)?
作者： Margaret McCann , Fidelma Fitzpatrick , George Mellotte , Michael Clarke
DOI: 10.1016/J.AJIC.2016.02.019
关键词: Relative risk 、 Anesthesia 、 Infection control 、 Hemodialysis 、 Medicine 、 Isopropyl alcohol 、 Confidence interval 、 Central venous catheter 、 Randomized controlled trial 、 Clinical trial
摘要: A pilot randomized trial in 3 Irish outpatient hemodialysis units compared 2% chlorhexidine gluconate (CHG) 70% isopropyl alcohol with routinely used CHG solutions for central venous catheter exit site antisepsis. We found no significant difference between the groups prevention of catheter-related bloodstream infections (1/53 vs 2/52; relative risk [RR], 0.49; 95% confidence interval [CI], 0.05-5.25; P = .55) and catheter-associated 4/52; RR, 0.25; CI, 0.03-2.12; = .16).
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