Self-Assembly of Okadaic Acid as a Pathway to the Cell
作者： Antonio Hernández Daranas , Patricia G. Cruz , Alberto Hernández Creus , Manuel Norte , José J. Fernández
DOI: 10.1021/OL701687M
关键词: Okadaic acid 、 Phosphatase 、 Threonine 、 Toxin 、 Membrane 、 Chemistry 、 Cell biology 、 Cell 、 Serine 、 Biochemistry 、 Toxin transport
摘要: The polyether toxin okadaic acid (OA) inhibits several protein serine/threonine phosphatases that play central roles in the regulation of many essential cellular processes. use scanning tunneling microscopy (STM) shows dimerization such toxins is crucial to understand mechanism transport across model membranes.
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