Use of cabergoline to treat primary and secondary anestrus in dogs

作者: Cristina Gobello , Gervasio Castex , Yanina Corrada

DOI: 10.2460/JAVMA.2002.220.1653

关键词: Serum progesteroneFollicular phaseEstrous cycleCabergolineProspective cohort studyMedicineOvulationPregnancyAdverse effectAnesthesia

摘要: Objective—To determine whether cabergoline would be safe and effective for induction of estrus in dogs with primary or secondary anestrus. Design—Prospective case series. Animals—6 privately owned otherwise healthy purebred Procedure—Dogs were treated (5 µg/kg [2.3 µg/lb], PO, q 24 h) until 2 days after the onset proestrus. Follicular development was assessed by means cytologic examination vaginal smears; ovulation measuring serum progesterone concentration 3 weeks estrus. Five bitches mated during behavioral Results—All had normal periods, all 5 that whelped litters. Mean duration treatment 16 days. None any adverse effects associated administration. Conclusions Clinical Relevance—Results suggest administration is anestr...

参考文章(8)
Ballabio R, D'Ver As, Jöchle W, Arbeiter K, Post K, Effects on pseudopregnancy, pregnancy and interoestrous intervals of pharmacological suppression of prolactin secretion in female dogs and cats. Journal of reproduction and fertility. ,vol. 39, pp. 199- 207 ,(1989)
P Jeukenne, J Verstegen, Termination of dioestrus and induction of oestrus in dioestrous nonpregnant bitches by the prolactin antagonist cabergoline. Journal of reproduction and fertility. ,vol. 51, pp. 59- 66 ,(1997)
Edward C. Feldman, Richard W. Nelson, Canine and Feline Endocrinology and Reproduction ,(1987)
K. Arbeiter, Evelin Barsch, Möglichkeiten der Läufigkeitsinduktion bei der Hündin mit einem Ergolin‐Derivat Journal of Veterinary Medicine Series A-physiology Pathology Clinical Medicine. ,vol. 35, pp. 111- 117 ,(1988) , 10.1111/J.1439-0442.1988.TB00012.X
Shirley D. Johnston, Clinical Approach to Infertility in Bitches with Primary Anestrus Veterinary Clinics of North America: Small Animal Practice. ,vol. 21, pp. 421- 425 ,(1991) , 10.1016/S0195-5616(91)50051-6
M. J. A. HARVEY, A. CAUVIN, M. DALE, S. Lindley, R. Ballabio, Effect and mechanisms of the anti-prolactin drug cabergoline on pseudopregnancy in the bitch. Journal of Small Animal Practice. ,vol. 38, pp. 336- 339 ,(1997) , 10.1111/J.1748-5827.1997.TB03480.X
A. C. Okkens, M. M. Bevers, S. J. Dieleman, A. H. Willems, Shortening of the interoestrous interval and the lifespan of the corpus luteum of the cyclic dog by bromocryptine treatment. Veterinary Quarterly. ,vol. 7, pp. 173- 176 ,(1985) , 10.1080/01652176.1985.9693979
J.P Verstegen, K Onclin, L.D.M Silva, P.W Concannon, Effect of stage of anestrus on the induction of estrus by the dopamine agonist cabergoline in dogs. Theriogenology. ,vol. 51, pp. 597- 611 ,(1999) , 10.1016/S0093-691X(99)00013-8