Genetic selection of sox1GFP-expressing neural precursors removes residual tumorigenic pluripotent stem cells and attenuates tumor formation after transplantation
作者： S. Chung , B.-S. Shin , E. Hedlund , J. Pruszak , A. Ferree
DOI: 10.1111/J.1471-4159.2006.03841.X
关键词: SOX2 、 Stem cell 、 Neurogenesis 、 Cellular differentiation 、 Biology 、 Embryonic stem cell 、 Induced pluripotent stem cell 、 Cell therapy 、 Cell sorting 、 Cell biology 、 Genetics
摘要: … We hypothesize that an efficient solution would consist of purifying the desired cell types, such as neural precursors, prior to transplantation. To test this hypothesis, we differentiated …
neuroregeneration.org 参考文章(52)
Hitoshi Fukuda, None, FACS-based purification of ES cell-derived neural precursors averts tumor formation after transplantation Kyoto University. ,(2006)
H. Michael Keyoung, Neeta S. Roy, Abdellatif Benraiss, Abner Louissaint, Akira Suzuki, Mitsuhiro Hashimoto, William K. Rashbaum, Hideyuki Okano, Steven A. Goldman, High-yield selection and extraction of two promoter-defined phenotypes of neural stem cells from the fetal human brain Nature Biotechnology. ,vol. 19, pp. 843- 850 ,(2001) , 10.1038/NBT0901-843
Janet Rossant, András Nagy, Elen Gócza, Elizabeth Merentes Diaz, Eszter Iványi, Merja Markkula, Valerie R. Prideaux, Embryonic stem cells alone are able to support fetal development in the mouse. Development. ,vol. 110, pp. 815- 821 ,(1990) , 10.1242/DEV.110.3.815
Stanley Tamaki, Karl Eckert, Dongping He, Richard Sutton, Monika Doshe, Gitanjali Jain, Robert Tushinski, Michael Reitsma, Brent Harris, Ann Tsukamoto, Fred Gage, Irving Weissman, Nobuko Uchida, None, Engraftment of sorted/expanded human central nervous system stem cells from fetal brain Journal of Neuroscience Research. ,vol. 69, pp. 976- 986 ,(2002) , 10.1002/JNR.10412
A. Nagy, J. Rossant, R. Nagy, W. Abramow-Newerly, J. C. Roder, Derivation of completely cell culture-derived mice from early-passage embryonic stem cells Proceedings of the National Academy of Sciences of the United States of America. ,vol. 90, pp. 8424- 8428 ,(1993) , 10.1073/PNAS.90.18.8424
Sang-Hun Lee, Nadya Lumelsky, Lorenz Studer, Jonathan M. Auerbach, Ron D. McKay, Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells Nature Biotechnology. ,vol. 18, pp. 675- 679 ,(2000) , 10.1038/76536
J DINSMORE, Embryonic stem cells differentiated in vitro as a novel source of cells for transplantation. Cell Transplantation. ,vol. 5, pp. 131- 143 ,(1996) , 10.1016/0963-6897(95)02040-3
Ling Wei, Lin Cui, B. Joy Snider, Mark Rivkin, Steven S. Yu, Chul-Sang Lee, Larry D. Adams, David I. Gottlieb, Eugene M. Johnson, Shan Ping Yu, Dennis W. Choi, Transplantation of embryonic stem cells overexpressing Bcl-2 promotes functional recovery after transient cerebral ischemia. Neurobiology of Disease. ,vol. 19, pp. 183- 193 ,(2005) , 10.1016/J.NBD.2004.12.016
Kirk R. Thomas, Mario R. Capecchi, Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells Cell. ,vol. 51, pp. 503- 512 ,(1987) , 10.1016/0092-8674(87)90646-5
Carlos Vicario-Abejón, Karl K. Johe, Thomas G. Hazel, Diana Collazo, Ronald D.G. McKay, FUNCTIONS OF BASIC FIBROBLAST GROWTH FACTOR AND NEUROTROPHINS IN THE DIFFERENTIATION OF HIPPOCAMPAL NEURONS Neuron. ,vol. 15, pp. 105- 114 ,(1995) , 10.1016/0896-6273(95)90068-3