Infections in Patients with Cancer: Overview

作者: Amar Safdar , Gerald Bodey , Donald Armstrong

DOI: 10.1007/978-1-60761-644-3_1

关键词: MedicineCancerAntimicrobialIntensive care medicineInfection controlHematopoietic stem cellIntervention (counseling)NeutropeniaImmune systemEpidemiology

摘要: Patients with neoplastic disease are often highly susceptible to severe infections. The following factors influence the types, severity, and response therapy of these infections: (1) Changing epidemiology infections; (2) cancer- and/or treatment-associated neutropenia; (3) acquired immune deficiency states such as cellular defect; (4) recent development new-generation diagnostic tools including widely available DNA amplification tests; (5) effective intervention for infection prevention; (6) empiric or presumptive during high-risk periods; (7) availability new classes active antimicrobial drugs; (8) strategies promote hosts’ response; (9) future measures. This introductory chapter intended reader become familiar important historical milestones in understanding field infectious diseases immunosuppressed patients an underlying neoplasms undergoing hematopoietic stem cell trans­plantation.

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