作者: Amar Safdar , Gerald Bodey , Donald Armstrong
DOI: 10.1007/978-1-60761-644-3_1
关键词: Medicine 、 Cancer 、 Antimicrobial 、 Intensive care medicine 、 Infection control 、 Hematopoietic stem cell 、 Intervention (counseling) 、 Neutropenia 、 Immune system 、 Epidemiology
摘要: Patients with neoplastic disease are often highly susceptible to severe infections. The following factors influence the types, severity, and response therapy of these infections: (1) Changing epidemiology infections; (2) cancer- and/or treatment-associated neutropenia; (3) acquired immune deficiency states such as cellular defect; (4) recent development new-generation diagnostic tools including widely available DNA amplification tests; (5) effective intervention for infection prevention; (6) empiric or presumptive during high-risk periods; (7) availability new classes active antimicrobial drugs; (8) strategies promote hosts’ response; (9) future measures. This introductory chapter intended reader become familiar important historical milestones in understanding field infectious diseases immunosuppressed patients an underlying neoplasms undergoing hematopoietic stem cell transplantation.