Sexual differentiation of the brain and ADHD: what is a sex difference in prevalence telling us?

摘要: Sexual differentiation of the brain is a function various processes that prepare organism for successful reproduction in adulthood. Release gonadal steroids during both perinatal and pubertal stages development organizes many sex differences, producing changes excitability morphology endure across lifespan. To achieve these sexual dimorphisms, capitalize on number distinct mechanisms regions. Comparison developing male female provides insight into through which synaptic connections are made, circuits organized mediate sexually dimorphic behaviors. The prevalence most psychiatric neurological disorders differ males versus females, including attention, activity impulse control. While there strong bias incidence attention deficit hyperactivity disorders, source remains controversial. By elucidating biological underpinnings development, we gain greater understanding how hormones genes do not contribute to differential vulnerability one other.