作者: Wendy E. Bloembergen , Austin G. Stack
DOI: 10.1681/ASN.V1271516
关键词: Kidney disease 、 Cardiology 、 Internal medicine 、 Myocardial infarction 、 Coronary artery disease 、 Cohort study 、 Population 、 Coronary artery bypass surgery 、 Surgery 、 Cross-sectional study 、 Angina 、 Medicine
摘要: Despite the high prevalence of coronary artery disease (CAD) among patients with end-stage renal (ESRD), few studies have identified clinical correlates using national data. The purpose this study was to determine and associations CAD in a random sample new ESRD United States 1996/1997 (n = 4025). Data on demographic characteristics comorbidities were obtained from Dialysis Morbidity Mortality Study, Wave 2. principal outcome CAD, defined as presence previous history myocardial infarction, or angina, bypass surgery, angioplasty, abnormal angiographic findings. Multivariate logistic regression analysis used assess relationship conventional factors proposed uremic CAD. present 38% patients. Of total cohort, 17% had infarction 23% angina. Several risk factors, including advancing age, male gender, diabetes mellitus, smoking, significantly associated lower serum albumin levels but higher residual function hematocrit values Vascular comorbid conditions, structural cardiac abnormalities, white race, geographic location also strongly correlated This suggests that several may be for population. identifies nonconventional such levels, vascular abnormalities important correlates. Future logitudinal are required explore relative importance relationships observed here.