作者: Michaela M. Pinter , Michael Brainin
DOI: 10.1159/000346433
关键词: Transcranial magnetic stimulation 、 Neuroscience 、 Stroke 、 Rehabilitation 、 Psychology 、 Physical medicine and rehabilitation 、 Neurophysiology 、 Deep transcranial magnetic stimulation 、 Cognition 、 Brain stimulation 、 Stroke recovery
摘要: In recent years, efforts have focused on investigating the neurophysiological changes that occur in brain after stroke, and developing novel strategies such as additional stimulation to enhance sensorimotor cognitive recovery. 1990s, repetitive transcranial magnetic (rTMS) was introduced a therapeutic tool for improving efficacy of rehabilitation recovery stroke. It is evident disturbances interhemispheric processes stroke result pathological hyperactivity intact hemisphere. The rationale using rTMS complementary therapy mainly decrease cortical excitability regions are presumed hinder optimal by low-frequency delivered unaffected hemisphere, while high-frequency affected hemisphere facilitates excitability. However, exact mechanisms how works still under investigation. There growing body research patients effect facilitating modifying subcortical networks. Clinical trials applying already yielded promising results functions. Altogether, combination with conventional approaches, has potential become strategy modulating targeted areas. future studies, emphasis should be placed selecting patient populations determine whether treatment response depends age, lesion acuteness, or severity. Furthermore, it important identify parameters optimizing beneficial effects recovery, monitor their long-term effects.