Vitamin D Metabolism and Profiling in Veterinary Species.
作者： Emma A. Hurst , Natalie Z. Homer , Richard J. Mellanby
关键词: Vitamin D metabolism 、 Single sample 、 Lc ms ms 、 Clinical Practice 、 Vitamin D+Metabolites 、 Metabolite 、 Biology 、 Liquid chromatography–mass spectrometry 、 Vitamin D and neurology 、 Veterinary medicine
摘要: The demand for vitamin D analysis in veterinary species is increasing with the growing knowledge of extra-skeletal role plays health and disease. circulating 25-hydroxyvitamin-D (25(OH)D) metabolite used to assess status, benefits analysing other metabolites complex pathway are being discovered humans. Profiling by liquid chromatography tandem mass spectrometry (LC-MS/MS) facilitates simultaneous multiple a single sample over wide dynamic ranges, this method now considered gold-standard quantifying metabolites. However, very few studies report using LC-MS/MS species. Given complexity similarities roles disease between humans companion animals, there clear need establish comprehensive, reliable that comparable human clinical practice. In review, we highlight differences metabolism measuring beyond 25(OH)D. Finally, discuss analytical challenges profiling focus on methods.
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Hedwig CM Stepman, An Vanderroost, Katleen Van Uytfanghe, Linda M Thienpont, Candidate Reference Measurement Procedures for Serum 25-Hydroxyvitamin D3 and 25-Hydroxyvitamin D2 by Using Isotope-Dilution Liquid Chromatography–Tandem Mass Spectrometry Clinical Chemistry. ,vol. 57, pp. 441- 448 ,(2011) , 10.1373/CLINCHEM.2010.152553
R.L. Horst, E.T. Littledike, Comparison of plasma concentrations of vitamin D and its metabolites in young and aged domestic animals Comparative Biochemistry and Physiology Part B: Comparative Biochemistry. ,vol. 73, pp. 485- 489 ,(1982) , 10.1016/0305-0491(82)90064-5
Glenville Jones, David E. Prosser, Martin Kaufmann, 25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): its important role in the degradation of vitamin D. Archives of Biochemistry and Biophysics. ,vol. 523, pp. 9- 18 ,(2012) , 10.1016/J.ABB.2011.11.003
Hans R. Rosenberg, The site and nature of provitamin D in birds Archives of Biochemistry and Biophysics. ,vol. 42, pp. 7- 11 ,(1953) , 10.1016/0003-9861(53)90232-X
Makoto Kakitani, Toshiro Fujita, Seiji Fukumoto, Takeyoshi Yamashita, Takashi Shimada, Hisashi Hasegawa, Yuji Yamazaki, Kazuma Tomizuka, Yasuhiro Takeuchi, Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism Journal of Clinical Investigation. ,vol. 113, pp. 561- 568 ,(2004) , 10.1172/JCI19081
K. C. Hutton, M. A. Vaughn, G. Litta, B. J. Turner, J. D. Starkey, Effect of vitamin D status improvement with 25-hydroxycholecalciferol on skeletal muscle growth characteristics and satellite cell activity in broiler chickens Journal of Animal Science. ,vol. 92, pp. 3291- 3299 ,(2014) , 10.2527/JAS.2013-7193
David C. Kersey, Martin Dehnhard, The use of noninvasive and minimally invasive methods in endocrinology for threatened mammalian species conservation. General and Comparative Endocrinology. ,vol. 203, pp. 296- 306 ,(2014) , 10.1016/J.YGCEN.2014.04.022
Paul Griffiths, Angela Fairney, Vitamin D metabolism in polar vertebrates. Comparative Biochemistry and Physiology B. ,vol. 91, pp. 511- 516 ,(1988) , 10.1016/0305-0491(88)90014-4
Fayez F. Safadi, Paul Thornton, Holly Magiera, Bruce W. Hollis, Michael Gentile, John G. Haddad, Stephen A. Liebhaber, Nancy E. Cooke, Osteopathy and resistance to vitamin D toxicity in mice null for vitamin D binding protein Journal of Clinical Investigation. ,vol. 103, pp. 239- 251 ,(1999) , 10.1172/JCI5244
Ann R. Webb, Who, what, where and when—influences on cutaneous vitamin D synthesis Progress in Biophysics & Molecular Biology. ,vol. 92, pp. 17- 25 ,(2006) , 10.1016/J.PBIOMOLBIO.2006.02.004