Common carotid intima-media thickness is predictive of all-cause and cardiovascular mortality in elderly community-dwelling people: Longitudinal Investigation for the Longevity and Aging in Hokkaido County (LILAC) study.

摘要: Several cohort studies have examined the association of carotid intima-media thickness (IMT) with risk stroke or myocardial infarction in apparently healthy persons. We investigated predictive value IMT cardiovascular mortality elderly community-dwelling people, beyond prediction provided by age and MMSE, assessed means a multivariate Cox model. Carotid plaque were evaluated bilaterally ultrasonography 298 people older than 75 years (120 men 178 women, average age: 79.6 years). The LILAC study started on July 25, 2000. Consultations repeated every year. follow-up ended November 30, 2004. During mean span 1152 days, 30 subjects (21 nine women) died. Nine deaths attributable to causes (myocardial infarction: two three women; stroke: women). age- MMSE-adjusted relative (RR) 95% confidence interval (95% CI) developing all-cause was assessed. A 0.3 mm increase left associated RR predicted 1.647 (1.075-2.524), similar right 3.327 (1.429-7.746). For mortality, corresponding values 2.351 (1.029-5.372) 2.890 (1.059-7.891), respectively. is positively an increased death people.