The emergence of drug transporter-mediated multidrug resistance to cancer chemotherapy.

作者: Chung-Pu Wu , Chia-Hung Hsieh , Yu-Shan Wu

DOI: 10.1021/MP200261N

关键词: Multidrug Resistance Protein 1Cancer researchDrugEffluxMultiple drug resistanceCancerATP-binding cassette transporterAbcg2PharmacologyBiologyABCC1

摘要: … initial chemotherapy and resulting in the MDR form of cancer. (4) The discovery of human … ATP to mediate drug transport has changed the perspective we have on drug resistance and …

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