Detection of Myocardial Perfusion in Multiple Echocardiographic Windows With One Intravenous Injection of Microbubbles Using Transient Response Second Harmonic Imaging

作者: Thomas R. Porter , Shouping Li , David Kricsfeld , Robert W. Armbruster

DOI: 10.1016/S0735-1097(96)00575-X

关键词: Cardiac cycleNuclear medicineMicrobubblesSecond-harmonic imaging microscopyPerfusion scanningUltrasoundPerfusionDipyridamoleThalliumMedicine

摘要: Abstract Objectives. The purpose of this study was to prove that transient response harmonic imaging could detect normal and abnormal myocardial perfusion in multiple echocardiographic windows with one intravenous injection microbubbles humans. Background. Myocardial ultrasound contrast can be produced from perfluorocarbon-exposed sonicated dextrose albumin, significantly improved by briefly suspending the interval between frame rates. Whether noninvasively quantify humans is unknown. Methods. In 28 patients, used image heart different planes after agent. Twenty-five these patients had a repeat during dipyridamole stress. primary view, transmission rate per cardiac cycle; secondary tertiary views, once every cycles. Regional visually assessed quantified off-line. Quantitative rest thallium stress sestamibi also performed. Results. Perfusion abnormalities were evident views only peak videointensity (PMVI) correlated closely regional tracer uptake individual both at (r = 0.84) 0.88). A PMVI ratio (abnormal region divided highest nuclear uptake) Conclusions. Transient produces agent accurately identify abnormalities. (J Am Coll Cardiol 1997;29:791–9)

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