Mithramycin encapsulated in polymeric micelles by microfluidic technology as novel therapeutic protocol for beta-thalassemia
作者： Claudio Nastruzzi , Capretto , Mazzitelli , Brognara , Lampronti
DOI: 10.2147/IJN.S25657
关键词: Plicamycin 、 K562 cells 、 Biophysics 、 Molecular biology 、 Micelle 、 Poloxamer 、 Drug 、 Biology 、 Cellular differentiation 、 Fetal hemoglobin 、 Erythroid Precursor Cells
摘要: This report shows that the DNA-binding drug, mithramycin, can be efficiently encapsulated in polymeric micelles (PM-MTH), based on Pluronic ® block copolymers, by a new …
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