Are antihistamine-decongestants of value in the treatment of acute otitis media in children?

摘要: Acute otitis media is the most common bacterial infection of childhood. The effectiveness oral antihistamine-decongestant mixtures in treatment this illness remains controversial clinical practice. In a double-blind randomized study, 82 children (aged under 15 years) with acute were treated amoxicillin and either decongestant-antihistamine mixture (Dimetapp) or placebo. All diagnoses required agreement between family practice resident supervising physician. Clinical course was assessed by symptom diaries completed parents follow-up examination at approximately two weeks, which included pneumatic otoscopy. No statistically significant benefit shown terms resolution symptoms prevention complications media. It recommended that antihistamine-decongestants not be routinely added to an antibiotic children.