作者: Holger Schulz , Hartwig Muhle
DOI: 10.1016/B978-012426400-7.50055-8
关键词: Respiration 、 Airway Hyper-Responsiveness 、 Respiratory physiology 、 Airway 、 Inhalation 、 Respiratory system 、 Neuroscience 、 Lung 、 Rat model 、 Immunology 、 Biology
摘要: Publisher Summary Respiration includes all processes involved in the transport of respiratory gases between environment and body tissues. The system, which is subject this chapter, provides for first steps - uptake oxygen- final steps- clearance carbon dioxide. system must continuously meet body's metabolic demands, even face other potentially competing tasks, e.g. phonation, olfaction, or acid-base regulation. This requires special structural features a high degree adaptability organs. Measurement techniques physiological ranges parameters mechanics, pulmonary ventilation, alveolar capillary gas exchange are introduced discussion. Because rats often used inhalation studies on health effects particulate matter, an overview particle deposition lung added. Finally, information airway reactivity rat models hyper responsiveness provided, since major feature many diseases.