作者: Diederik van de Beek , Eelco F.M. Wijdicks
DOI: 10.1016/S0072-9752(07)01716-2
关键词: Coma 、 Organ transplantation 、 Population 、 Level of consciousness 、 Transplantation 、 Neutropenia 、 Intensive care medicine 、 Medicine 、 Neurotoxicity 、 Sedation
摘要: Publisher Summary his chapter discusses the most commonly encountered causes of coma and other states altered awareness in transplant population. The underlying an abnormal conscious state or recipients depend on preoperative patient, type transplantation, use immunosuppressive drugs, rejection causing dysfunction graft behavior patient after organ transplant. Neurological consultation is required before transplantation. In recipients, acute confusional can be precipitated by withdrawal barbiturates alcohol, neurotoxicity from agents, high-dose corticosteroids at time treatment rejection. Brain death, a comatose with loss all brain function, uncommon recipients. Acute failure results serious, life-threatening condition heart, lung, liver, bone marrow Electrolyte disturbances occur frequently but rarely lead to seizures, decreased level consciousness, state. also gives account structural lesions. Seizures transplantation for seizures include metabolic electrolyte derangements, hypoxic-ischemic injury, cerebral lesions, central nervous system (CNS) infections. CNS infections population caused receipt infected associated neutropenia drugs. Accumulation sedation common cause become fully alert types. serious problem approach based several factors. Switching another agent has been risk