Erythropoietin-stimulating Agents in Chronic Kidney Disease: A Response to Hyporesponsiveness
作者： Patrick S. Parfrey
DOI: 10.1111/J.1525-139X.2011.00949.X
关键词: Immunology 、 Kidney disease 、 Medicine 、 Hemoglobin 、 Anemia 、 Erythropoietin 、 Maintenance therapy
摘要: Hyporesponsiveness to erythropoietin stimulating agents occurs frequently, and may be observed at initiation of treatment or during maintenance therapy. An inverse relationship between hyporesponsiveness incident cardiovascular events has been reported. It is related least in part co-morbidity its occurrence requires a search for the cause. Treatment anemia hyporesponsive patients should individualized, with consideration given indication ESA therapy, target hemoglobin maximal dose limitations.
sci-hub.se 参考文章(11)
Toto R Pfeffer MA, Burdmann EA, Chen CY, Cooper ME, de Zeeuw D, Eckardt KU, Feyzi JM, Ivanovich P, Kewalramani R, Levey AS, Lewis EF, McGill JB, McMurray JJ, Parfrey P, Parving HH, Remuzzi G, Singh AK, Solomon SD, TREAT Investigators.., None, A Trial of Darbepoetin Alfa in Type 2 Diabetes and Chronic Kidney Disease The New England Journal of Medicine. ,vol. 361, pp. 2019- 2032 ,(2009) , 10.1056/NEJMOA0907845
Shravanthi R. Gandra, Fredric O. Finkelstein, Antonia V. Bennett, Eldrin F. Lewis, Tracy Brazg, Mona L. Martin, Impact of Erythropoiesis-Stimulating Agents on Energy and Physical Function in Nondialysis CKD Patients With Anemia: A Systematic Review American Journal of Kidney Diseases. ,vol. 55, pp. 519- 534 ,(2010) , 10.1053/J.AJKD.2009.09.019
Kirsten L. Johansen, Fredric O. Finkelstein, Dennis A. Revicki, Matthew Gitlin, Christopher Evans, Tracy J. Mayne, Systematic Review and Meta-analysis of Exercise Tolerance and Physical Functioning in Dialysis Patients Treated With Erythropoiesis-Stimulating Agents American Journal of Kidney Diseases. ,vol. 55, pp. 535- 548 ,(2010) , 10.1053/J.AJKD.2009.12.018
Ajay K Singh, Lynda Szczech, Kezhen L Tang, Huiman Barnhart, Shelly Sapp, Marsha Wolfson, Donal Reddan, None, Correction of Anemia with Epoetin Alfa in Chronic Kidney Disease The New England Journal of Medicine. ,vol. 355, pp. 2085- 2098 ,(2006) , 10.1056/NEJMOA065485
Scott D Solomon, Hajime Uno, Eldrin F Lewis, Kai-Uwe Eckardt, Julie Lin, Emmanuel A Burdmann, Dick De Zeeuw, Peter Ivanovich, Andrew S Levey, Patrick Parfrey, Giuseppe Remuzzi, Ajay K Singh, Robert Toto, Fannie Huang, Jerome Rossert, John JV McMurray, Marc A Pfeffer, None, Erythropoietic response and outcomes in kidney disease and type 2 diabetes The New England Journal of Medicine. ,vol. 363, pp. 1146- 1155 ,(2010) , 10.1056/NEJMOA1005109
Robert N. Foley, Bryan M. Curtis, Patrick S. Parfrey, Erythropoietin Therapy, Hemoglobin Targets, and Quality of Life in Healthy Hemodialysis Patients: A Randomized Trial Clinical Journal of The American Society of Nephrology. ,vol. 4, pp. 726- 733 ,(2009) , 10.2215/CJN.04950908
Patrick S Parfrey, Robert N Foley, Barbara H Wittreich, Daniel J Sullivan, Martin J Zagari, Dieter Frei, None, Double-Blind Comparison of Full and Partial Anemia Correction in Incident Hemodialysis Patients without Symptomatic Heart Disease Journal of The American Society of Nephrology. ,vol. 16, pp. 2180- 2189 ,(2005) , 10.1681/ASN.2004121039
Tom Greene, John Daugirdas, Thomas Depner, Michael Allon, Gerald Beck, Cameron Chumlea, James Delmez, Frank Gotch, John W Kusek, Nathan Levin, William Owen, Gerald Schulman, Robert Star, Robert Toto, Garabed Eknoyan, Hemodialysis Study Group, Association of Achieved Dialysis Dose with Mortality in the Hemodialysis Study: An Example of “Dose-Targeting Bias” Journal of The American Society of Nephrology. ,vol. 16, pp. 3371- 3380 ,(2005) , 10.1681/ASN.2005030321
Suetonia C Palmer, Sankar D Navaneethan, Jonathan C Craig, David W Johnson, Marcello Tonelli, Amit X Garg, Fabio Pellegrini, Pietro Ravani, Meg Jardine, Vlado Perkovic, Giusi Graziano, Richard McGee, Antonio Nicolucci, Gianni Tognoni, Giovanni FM Strippoli, Meta-analysis: Erythropoiesis-Stimulating Agents in Patients With Chronic Kidney Disease Annals of Internal Medicine. ,vol. 153, pp. 23- 33 ,(2010) , 10.7326/0003-4819-153-1-201007060-00252
Tilman B. Drüeke, Francesco Locatelli, Naomi Clyne, Kai-Uwe Eckardt, Iain C. Macdougall, Dimitrios Tsakiris, Hans-Ulrich Burger, Armin Scherhag, Normalization of Hemoglobin Level in Patients with Chronic Kidney Disease and Anemia The New England Journal of Medicine. ,vol. 355, pp. 2071- 2084 ,(2006) , 10.1056/NEJMOA062276