Nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs.
作者： Takumi Satoh , Scott R. McKercher , Stuart A. Lipton
DOI: 10.1016/J.FREERADBIOMED.2013.07.022
关键词: Antioxidant Response Elements 、 Small molecule 、 Prodrug 、 Antioxidant 、 Biochemistry 、 KEAP1 、 Chemistry 、 Glutathione 、 Oxidative stress 、 Carnosol
摘要: … , and then activate the Keap1/Nrf2/ARE (antioxidant-response element) transcription … the Keap1/Nrf2/ARE pathway represents a promising drug target for these PED/PAT agents. …
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