Is dysplasia visible during surveillance colonoscopy in patients with ulcerative colitis
作者： Wojciech Blonski , Rabi Kundu , James Lewis , Faten Aberra , Mark Osterman
DOI: 10.1080/00365520701866150
关键词: Ulcerative colitis 、 Carcinoma 、 Colorectal cancer 、 Colonoscopy 、 Internal medicine 、 Dysplasia 、 Gastroenterology 、 Colitis 、 Medicine 、 Inflammatory bowel disease 、 Endoscopy
摘要: Objective. Patients with ulcerative colitis (UC) have an increased risk of developing colorectal cancer. It was widely believed that dysplastic lesions are invisible on colonoscopy and can only be detected by random biopsies, as 95% occur in flat colonic mucosa indistinct from surrounding tissue. The aim this study to determine whether dysplasia is visible during routine surveillance evaluating patients who had without overt carcinoma. Material methods. medical records, endoscopy pathology databases were systematically reviewed between 1997 2004 at the University Pennsylvania Health System. inflammatory bowel disease identified their charts reviewed. Results. Of 113 confirmed our center, 102 (90%) UC. Forty-nine (48%) UC underwent colonoscopic evaluation prior detection. This group select...
informahealthcare.com参考文章(33)
Daniel K. Podolsky, Inflammatory Bowel Disease New England Journal of Medicine. ,vol. 325, pp. 1008- 1016 ,(1991) , 10.1056/NEJM199110033251406
Ulrika Broomé, Greger Lindberg, Robert Löfberg, Primary sclerosing cholangitis in ulcerative colitis--a risk factor for the development of dysplasia and DNA aneuploidy? Gastroenterology. ,vol. 102, pp. 1877- 1880 ,(1992) , 10.1016/0016-5085(92)90308-L
Eric Rosenstock, Richard G. Farmer, Robert Petras, Michael V. Sivak, George B. Rankin, Benjamin H. Sullivan, Surveillance for colonic carcinoma in ulcerative colitis Gastroenterology. ,vol. 89, pp. 1342- 1346 ,(1985) , 10.1016/0016-5085(85)90653-5
Michael O. Blackstone, Robert H. Riddell, B.H.Gerald Rogers, Bernard Levin, Dysplasia-associated lesion or mass (DALM) detected by colonoscopy in long-standing ulcerative colitis: An indication for colectomy Gastroenterology. ,vol. 80, pp. 366- 374 ,(1981) , 10.1016/0016-5085(81)90727-7
Cyrus E. Rubin, Rodger C. Haggitt, Glenna C. Burmer, Teresa A. Brentnall, Allyn C. Stevens, Douglas S. Levine, Patrick J. Dean, Michael Kimmey, David R. Perera, Peter S. Rabinovitch, DNA aneuploidy in colonic biopsies predicts future development of dysplasia in ulcerative colitis. Gastroenterology. ,vol. 103, pp. 1611- 1620 ,(1992) , 10.1016/0016-5085(92)91185-7
David T. Rubin, Jami A. Rothe, Jeremy T. Hetzel, Russell D. Cohen, Stephen B. Hanauer, Are dysplasia and colorectal cancer endoscopically visible in patients with ulcerative colitis Gastrointestinal Endoscopy. ,vol. 65, pp. 998- 1004 ,(2007) , 10.1016/J.GIE.2006.09.025
F. Shanahan, W.M. Weinstein, C.N. Bernstein, Are we telling patients the truth about surveillance colonoscopy in ulcerative colitis The Lancet. ,vol. 343, pp. 71- 74 ,(1994) , 10.1016/S0140-6736(94)90813-3
Carlos Torres, Donald Antonioli, Robert D. Odze, Polypoid dysplasia and adenomas in inflammatory bowel disease: a clinical, pathologic, and follow-up study of 89 polyps from 59 patients The American Journal of Surgical Pathology. ,vol. 22, pp. 275- 284 ,(1998) , 10.1097/00000478-199803000-00001
Matthew Rutter, Brian Saunders, Kay Wilkinson, Steve Rumbles, Gillian Schofield, Michael Kamm, Christopher Williams, Ashley Price, Ian Talbot, Alastair Forbes, Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis Gastroenterology. ,vol. 126, pp. 451- 459 ,(2004) , 10.1053/J.GASTRO.2003.11.010
Per Karlen, Robert Lofberg, Olle Brostrom, Carl-Eric Leijonmarck, Goran Hellers, Per-Gunnar Persson, Increased risk of cancer in ulcerative colitis: a population-based cohort study. The American Journal of Gastroenterology. ,vol. 94, pp. 1047- 1052 ,(1999) , 10.1111/J.1572-0241.1999.01012.X