Tuberkulose der Lunge und Pleura im Alter

作者: Gerhard Hoheisel , Anne Hagert-Winkler , Jörg Winkler , Thomas Kahn , Arne C. Rodloff

DOI: 10.1007/S00063-009-1163-Y

关键词: DiseaseInternal medicineTuberculosisAdverse effectMedicineSurgeryIncidence (epidemiology)ComorbidityTuberculinPharmacotherapyImmunosuppression

摘要: With the increase of proportion elderly in total population more cases pulmonary and extrapulmonary tuberculosis (TB) are observed this age group as well. Symptoms TB unspecific, often less apparent elderly, may therefore cause a delay diagnostic process. A history comorbidities common elder compared to younger patients. The tuberculin skin test is frequently positive. interferon-gamma-release assay complementary together with clinical, radiologic, bacteriologic results helpful for diagnosis or exclusion an active latent infection. Medical treatment follows established guidelines same way likelihood drug-induced side effects interactions concomitant medications, however, increased. Comorbidity age-related immunosuppression lead healing Higher age, comorbidity, predictors increased mortality. Even low-incidence country like Germany, should be recognized explanation clinical symptoms particularly patient order allow early therapy thus reduction mortality prevention further spread disease.

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