Pressures generated within the chambers of the MagScrew TAH: an in vitro study.

作者: Christine R. Flick , Stephan Weber , Viviane Luangphakdy , Ryan S. Klatte , Kiyotaka Fukamachi

DOI: 10.1097/MAT.0B013E31815C8964

关键词: Pulmonary arteryPulsatile flowMaterials sciencePump chamberMean Aortic PressureReciprocating motionFuture studiesIn vitro studyArtificial heartBiomedical engineering

摘要: Incompetent inflow valves have been reported with clinical pulsatile left ventricular assist devices that use bioprosthetic valves. Suspected as the cause of premature valve failure within these devices, absolute pressures and instantaneous pressure changes were evaluated in MagScrew total artificial heart (TAH). The TAH is a passively filling pump which uses reciprocating magnetic actuating mechanism under various control modes to propel blood into circulation. Both right ejection speeds modulated optimized at onset hydraulic eject. These speed profiles vitro 220 beats per minute (bpm), 100% fill, mean aortic 100 mm Hg pulmonary artery 20 Hg. inside chambers was measured Millar Mikro-Tip catheter captured using Power Lab rate 40 kHz. chamber peak pressure, operating unmodified eject speeds, on average 183 for 133 right. Eject profiling both pumps reduced by 10% 28% pump, respectively. Future studies will assess software controlled optimization any condition how effective it vivo.

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