3-Amino-4-[5-(chloromethyl)-1,2,4-oxadiazol-3-yl]furazan –a multifunctional synthon for the synthesis of 1,2,5-oxadiazole derivatives
作者： Andrei I. Stepanov , Dmitry V. Dashko , Elena V. Stepanova
DOI: 10.1007/S10593-019-02607-1
关键词: Furazan 、 Synthon 、 Medicinal chemistry 、 Acylation 、 Chemistry 、 Ring (chemistry) 、 Oxadiazole 、 Reagent 、 Nitro 、 Organic chemistry
摘要: The chemical properties of 3-amino-4-[5-(chloromethyl)-1,2,4-oxadiazol-3-yl]furazan were scrutinized: acylation the amino group and its oxidation to azo nitro groups, reactions chloromethyl with N- S-nucleophilic reagents, as well transformation 1,2,4-oxadiazole ring.
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