Cardiac Adaptation in Acute Hypertensive Pulmonary Edema

作者: Andrei D. Mǎrgulescu , Roxana C. Rimbaş , Maria Florescu , Raluca E. Dulgheru , Mircea Cintezǎ

DOI: 10.1016/J.AMJCARD.2012.01.359

关键词: MedicineInternal medicineVentricular elastanceBasal (phylogenetics)Cardiac cycleAsymptomaticCardiologyAfterloadPulmonary edemaEjection fractionDiastole

摘要: The aim of this study was to evaluate the role left ventricular (LV) dysfunction (global and regional, systolic diastolic) acute dyssynchrony, ischemic mitral regurgitation (MR), afterload changes in hypertensive pulmonary edema (AHPE). Forty-four consecutive patients were evaluated by comprehensive echocardiography during clinical radiologic (63 ± 29 minutes after first dose treatment) 48 92 hours. Twenty age- gender-matched asymptomatic diabetic subjects served as controls. AHPE associated with increased (estimated arterial elastance 3.0 vs 2.3 mm Hg/ml, p = 0.024) subsequent decreased longitudinal LV function (mean strain 6 basal segments −11.0% −15.4%; 0.015) compared stable follow-up state. However, global maintained 1.7 1.6 stroke work 76.7 84.5 cJ, ejection fraction 0.33 0.37, all nonsignificant). Except for diastolic filling time (ratio cardiac cycle 0.41 0.49,

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