Activin and bone morphogenetic protein (BMP) signalling during tooth development

作者: Kristiina Heikinheimo , Catherine Bègue‐Kirn , Olli Ritvos , Timo Tuuri , Jean Victor Ruch

DOI: 10.1111/J.1600-0722.1998.TB02171.X

关键词: TGF beta signaling pathwayEndocrinologyACVR1Bone morphogenetic protein 10Cell biologyBone morphogenetic proteinACVR2BInternal medicineFollistatinActivin type 2 receptorsBiologyBMPR2

摘要: Activins and bone morphogenetic proteins (BMPs) belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related cytokines. Results recent in vivo vitro studies suggest that activin A, several BMPs, their cell surface receptors may participate tooth development. In addition, follistatin an extracellular protein interact with BMP signaling, appears be involved. This review focuses on advances relation roles activin/BMP receptors, ligands modifiers during

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