Mechanism of ribonuclease inhibition by ribonuclease inhibitor protein based on the crystal structure of its complex with ribonuclease A.

作者: Bostjan Kobe , Johann Deisenhofer

DOI: 10.1006/JMBI.1996.0694

关键词: RNase PRibonuclease IIIActive siteCrystallographyS-tagInhibitor proteinBiologyRibonucleaseConformational changeRibonuclease inhibitor

摘要: … One of the best characterized members of the LRR superfamily is ribonuclease inhibitor (RI), a cytoplasmic protein that tightly binds and inhibits ribonucleases (RNases) from the …

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