Fattori di crescita e cartilagine

作者: A. Gigante , A. Busilacchi , S. Cecconi , F. Greco

DOI: 10.1007/S10261-009-0042-7

关键词: Articular cartilage repairCartilage metabolismMedicineAnatomyBioinformaticsCartilage

摘要: Growth factors play an important role in articular cartilage repair and they represent a therapeutic resource for the future. In following manuscript we describe most relevant growth metabolism, their biochemical features physio-pathology.

参考文章(79)
Stephen Trippel, Growth factor actions on articular cartilage. The Journal of Rheumatology Supplement. ,vol. 43, pp. 129- 132 ,(1995)
STEPHEN D. COOK, LAURA P. PATRON, SAMANTHA L. SALKELD, DAVID C. RUEGER, Repair of articular cartilage defects with osteogenic protein-1 (BMP-7) in dogs. Journal of Bone and Joint Surgery, American Volume. ,vol. 85, pp. 116- 123 ,(2003) , 10.2106/00004623-200300003-00018
P M van der Kraan, O J Arntz, W B van den Berg, H M van Beuningen, Transforming growth factor-beta 1 stimulates articular chondrocyte proteoglycan synthesis and induces osteophyte formation in the murine knee joint. Laboratory Investigation. ,vol. 71, pp. 279- 290 ,(1994)
V M Paralkar, A K Nandedkar, R H Pointer, H K Kleinman, A H Reddi, Interaction of osteogenin, a heparin binding bone morphogenetic protein, with type IV collagen. Journal of Biological Chemistry. ,vol. 265, pp. 17281- 17284 ,(1990) , 10.1016/S0021-9258(17)44900-3
P.M. van der Kraan, F.P.J.G. Lafeber, H.L.A.M. van Roy, W.B. van den Berg, J.W.J. Bijlsma, Transforming growth factor-beta predominantly stimulates phenotypically changed chondrocytes in osteoarthritic human cartilage. The Journal of Rheumatology. ,vol. 24, pp. 536- 542 ,(1997)
P V Hauschka, A E Mavrakos, M D Iafrati, S E Doleman, M Klagsbrun, Growth factors in bone matrix. Isolation of multiple types by affinity chromatography on heparin-Sepharose Journal of Biological Chemistry. ,vol. 261, pp. 12665- 12674 ,(1986) , 10.1016/S0021-9258(18)67143-1
S C Chang, B Hoang, J T Thomas, S Vukicevic, F P Luyten, N J Ryba, C A Kozak, A H Reddi, M Moos, Cartilage-derived morphogenetic proteins. New members of the transforming growth factor-beta superfamily predominantly expressed in long bones during human embryonic development. Journal of Biological Chemistry. ,vol. 269, pp. 28227- 28234 ,(1994) , 10.1016/S0021-9258(18)46918-9
J.M. Hurle, M.A. Ros, Y. Ganan, D. Macias, M.E. Piedra, T.K. Sampath, Role of BMP-2 and OP-1 (BMP-7) in programmed cell death and skeletogenesis during chick limb development Development. ,vol. 124, pp. 1109- 1117 ,(1997) , 10.1242/DEV.124.6.1109
R. Montesano, J. D. Vassalli, A. Baird, R. Guillemin, L. Orci, Basic fibroblast growth factor induces angiogenesis in vitro. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 83, pp. 7297- 7301 ,(1986) , 10.1073/PNAS.83.19.7297
Per Aspenberg, Karl-Göran Thorngren, L. Stefan Lohmander, Dose-dependent stimulation of bone induction by basic fibroblast growth factor in rats. Acta Orthopaedica Scandinavica. ,vol. 62, pp. 481- 484 ,(1991) , 10.3109/17453679108996650