Cone snail venomics: From novel biology to novel therapeutics
作者： Jutty Rajan Prashanth , Andreas Brust , Ai-Hua Jin , Paul F Alewood , Sébastien Dutertre
DOI: 10.4155/FMC.14.99
关键词: Computational biology 、 Cone snail 、 Drug discovery 、 Conotoxin 、 Bioinformatics 、 Biology
摘要: … For example, the calcium channel blocker ω-MVIIA (Prialt) [10] has a VI/VII framework incorporating an inhibitory cysteine knot [20]. α-Vc1.1, which targets nicotinic acetylcholine …
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