Genetic Diversity of Enteric Viruses in Children under Five Years Old in Gabon.

摘要: Enteric viruses are the leading cause of diarrhea in children globally. Identifying viral agents and understanding their genetic diversity could help to develop effective preventive measures. This study aimed determine detection rate four enteric Gabonese aged below five years. Stool samples from <5 years with (n = 177) without 67) were collected April 2018 November 2019. Norovirus, astrovirus, sapovirus, aichivirus A identified using PCR techniques followed by sequencing phylogenetic analyses. At least one agent was 23.2% 14.9% symptomatic asymptomatic participants, respectively. Norovirus (14.7%) astrovirus (7.3%) most prevalent diarrhea, whereas healthy group norovirus (9%) first reported Gabon (6%) predominant. The predominant genogroup GII, consisting mostly genotype GII.P31-GII.4 Sydney. Phylogenetic analysis 3CD region genome revealed presence two genotypes (A C) cohort. Astrovirus sapovirus showed a high diversity, different genotypes, Our findings give new insights into circulation children.