Depressed mood and body mass index as predictors of muscle strength decline in old men

摘要: OBJECTIVE: To study depressed mood as a predictor of strength decline within body weight categories over 3-year follow-up period. DESIGN: A prospective cohort 3 years. SETTING: Honolulu, Hawaii. PARTICIPANTS: The subjects were 2275 men participating in the Honolulu Heart Program with an average age 77.1 years (range 71–92 years), who not cognitively impaired at baseline (Exam 4), and participated maximal hand grip measurements later 5). MEASUREMENTS: Hand was measured using dynamometer. Depressive symptoms studied 11-item version Center for Epidemiologic Studies Depression Scale 9 cutoff. Body formed on basis mass index (BMI) (BMI = weight/height2; underweight: BMI < 20; normal weight: 20–24.99, overweight: ≥ 25). MAIN RESULTS: At baseline, 9.4% participants rated having mood. mean individual change −6.9% (standard deviation 14.0). Steep determined losing ≥14% (lowest quartile). proportions those steep groups based combined distributions were: underweight/depressed (n 22) 41%, underweight/not 200) 28%, weight/depressed 127) 30%, weight/not 1181) 25%, overweight/depressed 55) 31%, overweight/not 675, referent) 21%. After adjusting strength, age, height, sociodemographic variables diseases, odds ratio more than four times greater among underweight, twice great people compared nondepressed overweight. risks under- overweight did differ from reference group. CONCLUSIONS: Depressed associated increased risk decline, particular older low weight. Low combination may be indicator frailty or severe disease status that leads to accelerated loss disability. J Am Geriatr Soc 48:613–617, 2000.