Identification of galactitol 2-phosphate and galactitol 3-phosphate in the lens of galactose-fed rats
作者： Francis Kappler , Bangying Su , Benjamin S. Szwergold , William C. Randall , Truman R. Brown
DOI: 10.1016/0026-0495(95)90069-1
关键词: Metabolite 、 Endocrinology 、 Sorbitol 、 Biology 、 Galactitol 、 Internal medicine 、 Fructose 、 Pentose phosphate pathway 、 Galactose 、 Sedoheptulose 、 Aldose reductase 、 Biochemistry
摘要: … derivatives of galactitol as Gal-2P and Gal-3P in lenses of galactose-fed rats. In addition, … As expected, the overwhelming change observed is the increase in galactitol concentration …
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sci-hub.se 参考文章(24)
Nalin Unakar, Jane Tsui, Margaret Johnson, None, Aldose reductase inhibitors and prevention of galactose cataracts in rats Investigative Ophthalmology & Visual Science. ,vol. 30, pp. 1623- 1632 ,(1989)
S. Lal, B.S. Szwergold, F. Kappler, T. Brown, Detection of fructose-3-phosphokinase activity in intact mammalian lenses by 31P NMR spectroscopy Journal of Biological Chemistry. ,vol. 268, pp. 7763- 7767 ,(1993) , 10.1016/S0021-9258(18)53023-4
B S Szwergold, F Kappler, T R Brown, P Pfeffer, S F Osman, Identification of D-Sorbitol 3-Phosphate in the Normal and Diabetic Mammalian Lens Journal of Biological Chemistry. ,vol. 264, pp. 9278- 9282 ,(1989) , 10.1016/S0021-9258(18)60526-5
D.G. Dyer, J.A. Blackledge, S.R. Thorpe, J.W. Baynes, Formation of pentosidine during nonenzymatic browning of proteins by glucose. Identification of glucose and other carbohydrates as possible precursors of pentosidine in vivo. Journal of Biological Chemistry. ,vol. 266, pp. 11654- 11660 ,(1991) , 10.1016/S0021-9258(18)99007-1
A Petersen, F Kappler, B S Szwergold, T R Brown, Fructose metabolism in the human erythrocyte. Phosphorylation to fructose 3-phosphate Biochemical Journal. ,vol. 284, pp. 363- 366 ,(1992) , 10.1042/BJ2840363
Ruth van Heyningen, The sorbitol pathway in the lens Experimental Eye Research. ,vol. 1, pp. 396- 404 ,(1962) , 10.1016/S0014-4835(62)80029-3
Hong-Ming Cheng, Jing Xiong, George Tanaka, Chen Chang, Alexander A Asterlin, James B Aguayo, None, Analysis of concurrent glucose consumption by the hexose monophosphate shunt, glycolysis, and the polyol pathway in the crystalline lens. Experimental Eye Research. ,vol. 53, pp. 363- 366 ,(1991) , 10.1016/0014-4835(91)90242-7
J.H. Kinoshita, S. Futterman, K. Satoh, L.O. Merola, Factors affecting the formation of sugar alcohols in ocular lens Biochimica et Biophysica Acta. ,vol. 74, pp. 340- 350 ,(1963) , 10.1016/0006-3002(63)91377-5
M.S. Swamy, C. Tsai, A. Abraham, E.C. Abraham, Glycation Mediated Lens Crystallin Aggregation and Cross-linking by Various Sugars and Sugar Phosphates In Vitro Experimental Eye Research. ,vol. 56, pp. 177- 185 ,(1993) , 10.1006/EXER.1993.1025
B. Szwergold, F Kappler, T. Brown, Identification of fructose 3-phosphate in the lens of diabetic rats. Science. ,vol. 247, pp. 451- 454 ,(1990) , 10.1126/SCIENCE.2300805