Innocuité des anticorps monoclonaux pour le manipulateur : mythe ou réalité ? A propos d’une enquête de pratiques professionnelles
作者： S Pigneret-Bernard , G Saint-Lorant , F Divanon
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摘要: La preparation des chimiotherapies anticancereuses conventionnelles presente un risque pour le manipulateur. Par analogie, il est legitime de s’interroger sur ce lors la manipulation anticorps monoclonaux. Dans cette optique, une enquete nationale pratiques monoclonaux a ete realisee. Les resultats ont confrontes aux donnees litterature. L’enquete revele les interrogations partagees par nombreux pharmaciens quant l’innocuite Elle montre egalement que si centralisation realisee raisons economiques et securitaires dans etablissements, aucune separation lignes production n’est effectuee entre conventionnelles. bibliographiques proprietes physicochimiques sont en faveur d’un faible professionnel. Afin d’eviter tout contamination croisee, apparait souhaitable separer produits ayant potentiel carcinogene different selon classification l’International Agency for Research on Cancer. dissociation circuits pose neanmoins probleme faisabilite termes ressources humaines materielles. Une reflexion doit etre menee au regard nouvelles therapeutiques dont toxicite manipulateur semble different.
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