The right chance for temozolomide in metastatic colorectal cancer

作者: A. Sartore-Bianchi , S. Siena

DOI: 10.1093/ANNONC/MDY223

关键词: MedicineText miningInternal medicineTemozolomideOncologyColorectal cancer

摘要:

参考文章(14)
Alessio Amatu, Andrea Sartore-Bianchi, Catia Moutinho, Alessandro Belotti, Katia Bencardino, Giuseppe Chirico, Andrea Cassingena, Francesca Rusconi, Anna Esposito, Michele Nichelatti, Manel Esteller, Salvatore Siena, Promoter CpG Island Hypermethylation of the DNA Repair Enzyme MGMT Predicts Clinical Response to Dacarbazine in a Phase II Study for Metastatic Colorectal Cancer Clinical Cancer Research. ,vol. 19, pp. 2265- 2272 ,(2013) , 10.1158/1078-0432.CCR-12-3518
Stephen B. Baylin, James G. Herman, Stanley R. Hamilton, Peter C. Burger, Manel Esteller, Inactivation of the DNA Repair Gene O6-Methylguanine-DNA Methyltransferase by Promoter Hypermethylation is a Common Event in Primary Human Neoplasia Cancer Research. ,vol. 59, pp. 793- 797 ,(1999)
F. Pietrantonio, F. Perrone, F. de Braud, A. Castano, C. Maggi, I. Bossi, A. Gevorgyan, P. Biondani, M. Pacifici, A. Busico, M. Gariboldi, F. Festinese, E. Tamborini, M. Di Bartolomeo, Activity of temozolomide in patients with advanced chemorefractory colorectal cancer and MGMT promoter methylation Annals of Oncology. ,vol. 25, pp. 404- 408 ,(2014) , 10.1093/ANNONC/MDT547
Gabriel Capella, Minoru Toyota, Manel Esteller, David Sidransky, Montserrat Sanchez-Cespedes, Stephen B. Baylin, Miguel Angel Peinado, Jean Pierre J. Issa, James G. Herman, D. Neil Watkins, Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis. Cancer Research. ,vol. 60, pp. 2368- 2371 ,(2000)
Filippo Pietrantonio, Filippo de Braud, Massimo Milione, Claudia Maggi, Roberto Iacovelli, Katia Fiorella Dotti, Federica Perrone, Elena Tamborini, Marta Caporale, Rosa Berenato, Giorgia Leone, Alessio Pellegrinelli, Ilaria Bossi, Fabrizio Festinese, Stefano Federici, Maria Di Bartolomeo, Dose-Dense Temozolomide in Patients with MGMT-Silenced Chemorefractory Colorectal Cancer Targeted Oncology. ,vol. 11, pp. 337- 343 ,(2016) , 10.1007/S11523-015-0397-2
Rodrigo Dienstmann, Danila Serpico, Jordi Rodon, Cristina Saura, Teresa Macarulla, Elena Elez, Maria Alsina, Jaume Capdevila, Jose Perez-Garcia, Gessamí Sánchez-Ollé, Claudia Aura, Ludmila Prudkin, Stefania Landolfi, Javier Hernández-Losa, Ana Vivancos, Josep Tabernero, None, Molecular Profiling of Patients with Colorectal Cancer and Matched Targeted Therapy in Phase I Clinical Trials Molecular Cancer Therapeutics. ,vol. 11, pp. 2062- 2071 ,(2012) , 10.1158/1535-7163.MCT-12-0290
A. Amatu, L. Barault, C. Moutinho, A. Cassingena, K. Bencardino, S. Ghezzi, L. Palmeri, E. Bonazzina, F. Tosi, R. Ricotta, T. Cipani, P. Crivori, R. Gatto, G. Chirico, G. Marrapese, M. Truini, A. Bardelli, M. Esteller, F. Di Nicolantonio, A. Sartore-Bianchi, S. Siena, Tumor MGMT promoter hypermethylation changes over time limit temozolomide efficacy in a phase II trial for metastatic colorectal cancer Annals of Oncology. ,vol. 27, pp. 1062- 1067 ,(2016) , 10.1093/ANNONC/MDW071
Andrea Sartore-Bianchi, Filippo Pietrantonio, Alessio Amatu, Massimo Milione, Andrea Cassingena, Silvia Ghezzi, Marta Caporale, Rosa Berenato, Chiara Falcomatà, Alessio Pellegrinelli, Alberto Bardelli, Michele Nichelatti, Federica Tosi, Filippo De Braud, Federica Di Nicolantonio, Ludovic Barault, Salvatore Siena, Digital PCR assessment of MGMT promoter methylation coupled with reduced protein expression optimises prediction of response to alkylating agents in metastatic colorectal cancer patients European Journal of Cancer. ,vol. 71, pp. 43- 50 ,(2017) , 10.1016/J.EJCA.2016.10.032
Rodrigo Dienstmann, Louis Vermeulen, Justin Guinney, Scott Kopetz, Sabine Tejpar, Josep Tabernero, Consensus molecular subtypes and the evolution of precision medicine in colorectal cancer Nature Reviews Cancer. ,vol. 17, pp. 79- 92 ,(2017) , 10.1038/NRC.2016.126
M A Calegari, A Inno, S Monterisi, A Orlandi, D Santini, M Basso, A Cassano, M Martini, T Cenci, I de Pascalis, F Camarda, B Barbaro, L M Larocca, S Gori, G Tonini, C Barone, A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation British Journal of Cancer. ,vol. 116, pp. 1279- 1286 ,(2017) , 10.1038/BJC.2017.109