Tuning in to the signals: noncoding sequence conservation in vertebrate genomes

作者: Greg Elgar , Tanya Vavouri

DOI: 10.1016/J.TIG.2008.04.005

关键词: GenomeGeneticsComparative genomicsMolecular evolutionBiologyEvolutionary biologySequence (medicine)Conserved sequenceENCODEConserved non-coding sequenceRegulatory sequence

摘要: … We discuss the relative merits of using sequence conservation as a tool in identifying regulatory sequences and how this approach can be refined in light of recent literature. …

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