Population pharmacokinetics, safety and dosing optimization of voriconazole in patients with liver dysfunction: A prospective observational study.
作者： Dan Tang , Miao Yan , Bai‐li Song , Yi‐chang Zhao , Yi‐wen Xiao
DOI: 10.1111/BCP.14578
关键词: Voriconazole 、 TBIL 、 Medicine 、 Gastroenterology 、 Internal medicine 、 Loading dose 、 Pharmacokinetics 、 Population 、 Volume of distribution 、 Maintenance dose 、 Dosing
摘要: … antifungal agent for the treatment of invasive fungal infections… halved in patients with mild-to-moderate liver disease (Child–… dysfunction based on our PPK model and TBIL …
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