Migraine classification using magnetic resonance imaging resting-state functional connectivity data

作者: Catherine D Chong , Nathan Gaw , Yinlin Fu , Jing Li , Teresa Wu

DOI: 10.1177/0333102416652091

关键词: Functional connectivityResting state fMRIMagnetic resonance imagingInsulaNeuroimagingMigraineAmygdalaMedicineHealthy controlAudiologyNeuroscience

摘要: BackgroundThis study used machine-learning techniques to develop discriminative brain-connectivity biomarkers from resting-state functional magnetic resonance neuroimaging (rs-fMRI) data that distinguish between individual migraine patients and healthy controls.MethodsThis included 58 (mean age = 36.3 years; SD = 11.5) 50 controls age = 35.9 SD = 11.0). The connections of 33 seeded pain-related regions were as input for a brain classification algorithm tested the accuracy determining whether an MRI belongs someone with or control.ResultsThe best using 10-fold cross-validation method was 86.1%. Resting connectivity right middle temporal, posterior insula, cingulate, left ventromedial prefrontal bilateral amygdala discriminated control. Migraineurs longer disease durations cla...

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