Calyceramides A–C: neuraminidase inhibitory sulfated ceramides from the marine sponge Discodermia calyx 1
作者： Yoichi Nakao , Kentaro Takada , Shigeki Matsunaga , Nobuhiro Fusetani
DOI: 10.1016/S0040-4020(01)00163-6
关键词: Neuraminidase 、 Calyx 、 Chemistry 、 Biochemistry 、 Stereochemistry 、 Inhibitory postsynaptic potential 、 Discodermia 、 Sulfation 、 Sponge
摘要: Abstract Three new sulfated ceramides, calyceramides A–C ( 1 – 3 ) were isolated as inhibitors of neuraminidase from the marine sponge Discodermia calyx . Their structures determined by spectroscopic and chemical methods. The ceramides inhibited with IC 50 values 0.2–0.8 μg mL −1
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