Metabolic regulation of peroxisomal and mitochondrial fatty acid oxidation
作者： Christiane Van Den Branden , Joseph Vamecq
DOI: 10.1007/978-1-4419-9072-3_40
关键词: Metabolic pathway 、 Biochemistry 、 Lipid metabolism 、 Peroxisome 、 Carbohydrate 、 Very long chain fatty acid 、 Mitochondrion 、 Chemistry 、 Beta oxidation 、 Adipose tissue
摘要: Glucose and fatty acids are the major metabolic fuels for cell. Cells possess entire set of genes carbohydrate fat metabolism. Depending on fuel levels, induced hormone secretion cross talk between pathways, cells choose glucose acid breakdown to provide their energy. During fasting large amounts free by adipose tissue, glucagon level rises oxidation is favoured. Fatty broken down in mitochondria peroxisomes. Mitochondria can fully degrade into acetyl-CoA units (and eventually C02 water Krebs cycle); peroxisomes only chain-shorten produce H202 this process. In paper, aspects short term (metabolic) regulation discussed.
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