THERMAL DESTRUCTION OF FOLACIN: EFFECT OF ASCORBIC ACID, OXYGEN AND TEMPERATURE

作者: T.-S. CHEN , R.G. COOPER

DOI: 10.1111/J.1365-2621.1979.TB08483.X

关键词: Inorganic chemistryOxygenTetrahydrofolic acidReducing agentActivation energyAscorbic acidAqueous solutionThermal stabilityChemistryArrhenius equation

摘要: The effects of temperature and the presence oxygen reducing agent on thermal stability two naturally occurring labile folates were investigated Microbiological assay samples heated from 49–100°C for various lengths time revealed that loss 5-methyltetrahydrofolic acid in aqueous solution followed first order kinetics with a low Arrhenius activation energy 9.5 kcal/mole. Tetrahydrofolic was extremely during heating both forms folate increased ascorbate nitrogen atmosphere.

参考文章(14)
Cooper Rg, King Ma, Chen Ts, Thermal destruction of folacin in microwave and conventional heating. Journal of The American Dietetic Association. ,vol. 73, pp. 406- ,(1978)
J D O’Broin, I J Temperley, J P Brown, J M Scott, Nutritional stability of various naturally occurring monoglutamate derivatives of folic acid The American Journal of Clinical Nutrition. ,vol. 28, pp. 438- 444 ,(1975) , 10.1093/AJCN/28.5.438
Margaret IB Dick, Isobel T Harrison, KTH Farrer, The thermal stability of folic (pteroylglutamic) acid. Immunology and Cell Biology. ,vol. 26, pp. 239- 244 ,(1948) , 10.1038/ICB.1948.25
A. H. Waters, D. L. Mollin, J. Pope, T. Towler, Studies on the folic acid activity of human serum. Journal of Clinical Pathology. ,vol. 14, pp. 335- 344 ,(1961) , 10.1136/JCP.14.4.335
B. PAINE-WILSON, T. -S. CHEN, THERMAL DESTRUCTION OF FOLACIN: EFFECT OF pH AND BUFFER IONS Journal of Food Science. ,vol. 44, pp. 717- 722 ,(1979) , 10.1111/J.1365-2621.1979.TB08484.X
D. J. HAMM, D. B. LUND, KINETIC PARAMETERS FOR THERMAL INACTIVATION OF PANTOTHENIC ACID Journal of Food Science. ,vol. 43, pp. 631- 633 ,(1978) , 10.1111/J.1365-2621.1978.TB02371.X
Edward R. Garrett, Prediction of stability in pharmaceutical preparations II. Vitamin stability in liquid multivitamin preparations Journal of the American Pharmaceutical Association. ,vol. 45, pp. 171- 178 ,(1956) , 10.1002/JPS.3030450313
Theodore P. Labuza, Steven R. Tannenbaum, Nutrient losses during drying and storage of dehydrated foods Critical Reviews in Food Science and Nutrition. ,vol. 3, pp. 217- 240 ,(1972) , 10.1080/10408397209527139
T. Tamura, Y.S. Shin, M.A. Williams, E.L.R. Stokstad, Lactobacillus casei response to pteroylpolyglutamates Analytical Biochemistry. ,vol. 49, pp. 517- 521 ,(1972) , 10.1016/0003-2697(72)90456-3