Non–Small Cell Lung Cancer, PD-L1, and the Pathologist

R Jeffrey, S K Johnson, J Weir, G King, K M Kerr, M M Kennedy, Partial regression in primary carcinoma of the lung: does it occur? Histopathology. ,vol. 33, pp. 55- 63 ,(1998) , 10.1046/J.1365-2559.1998.00453.X

Edward B Garon, Naiyer A Rizvi, Rina Hui, Natasha Leighl, Ani S Balmanoukian, Joseph Paul Eder, Amita Patnaik, Charu Aggarwal, Matthew Gubens, Leora Horn, Enric Carcereny, Myung-Ju Ahn, Enriqueta Felip, Jong-Seok Lee, Matthew D Hellmann, Omid Hamid, Jonathan W Goldman, Jean-Charles Soria, Marisa Dolled-Filhart, Ruth Z Rutledge, Jin Zhang, Jared K Lunceford, Reshma Rangwala, Gregory M Lubiniecki, Charlotte Roach, Kenneth Emancipator, Leena Gandhi, None, Pembrolizumab for the treatment of non-small cell lung cancer The New England Journal of Medicine. ,vol. 372, pp. 2018- 2028 ,(2015) , 10.1056/NEJMOA1501824

Stéphane Champiat, Ecaterina Ileana, Giuseppe Giaccone, Benjamin Besse, Giannis Mountzios, Alexander Eggermont, Jean-Charles Soria, Incorporating Immune-Checkpoint Inhibitors into Systemic Therapy of NSCLC Journal of Thoracic Oncology. ,vol. 9, pp. 144- 153 ,(2014) , 10.1097/JTO.0000000000000074

Ching-Yao Yang, Mong-Wei Lin, Yih-Leong Chang, Chen-Tu Wu, Pan-Chyr Yang, Programmed cell death-ligand 1 expression in surgically resected stage I pulmonary adenocarcinoma and its correlation with driver mutations and clinical outcomes. European Journal of Cancer. ,vol. 50, pp. 1361- 1369 ,(2014) , 10.1016/J.EJCA.2014.01.018

R. D. Schreiber, L. J. Old, M. J. Smyth, Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion Science. ,vol. 331, pp. 1565- 1570 ,(2011) , 10.1126/SCIENCE.1203486

Michael S Lawrence, Petar Stojanov, Paz Polak, Gregory V Kryukov, Kristian Cibulskis, Andrey Sivachenko, Scott L Carter, Chip Stewart, Craig H Mermel, Steven A Roberts, Adam Kiezun, Peter S Hammerman, Aaron McKenna, Yotam Drier, Lihua Zou, Alex H Ramos, Trevor J Pugh, Nicolas Stransky, Elena Helman, Jaegil Kim, Carrie Sougnez, Lauren Ambrogio, Elizabeth Nickerson, Erica Shefler, Maria L Cortés, Daniel Auclair, Gordon Saksena, Douglas Voet, Michael Noble, Daniel DiCara, Pei Lin, Lee Lichtenstein, David I Heiman, Timothy Fennell, Marcin Imielinski, Bryan Hernandez, Eran Hodis, Sylvan Baca, Austin M Dulak, Jens Lohr, Dan-Avi Landau, Catherine J Wu, Jorge Melendez-Zajgla, Alfredo Hidalgo-Miranda, Amnon Koren, Steven A McCarroll, Jaume Mora, Ryan S Lee, Brian Crompton, Robert Onofrio, Melissa Parkin, Wendy Winckler, Kristin Ardlie, Stacey B Gabriel, Charles WM Roberts, Jaclyn A Biegel, Kimberly Stegmaier, Adam J Bass, Levi A Garraway, Matthew Meyerson, Todd R Golub, Dmitry A Gordenin, Shamil Sunyaev, Eric S Lander, Gad Getz, None, Mutational heterogeneity in cancer and the search for new cancer-associated genes Nature. ,vol. 499, pp. 214- 218 ,(2013) , 10.1038/NATURE12213

Julie R. Brahmer, Charles G. Drake, Ira Wollner, John D. Powderly, Joel Picus, William H. Sharfman, Elizabeth Stankevich, Alice Pons, Theresa M. Salay, Tracee L. McMiller, Marta M. Gilson, Changyu Wang, Mark Selby, Janis M. Taube, Robert Anders, Lieping Chen, Alan J. Korman, Drew M. Pardoll, Israel Lowy, Suzanne L. Topalian, Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates Journal of Clinical Oncology. ,vol. 28, pp. 3167- 3175 ,(2010) , 10.1200/JCO.2009.26.7609

Senga K Johnson, Keith M Kerr, Andrea D Chapman, Margaret M Kennedy, George King, John S Cockburn, Robert R Jeffrey, Immune cell infiltrates and prognosis in primary carcinoma of the lung. Lung Cancer. ,vol. 27, pp. 27- 35 ,(2000) , 10.1016/S0169-5002(99)00095-1

Vamsidhar Velcheti, Kurt A Schalper, Daniel E Carvajal, Valsamo K Anagnostou, Konstantinos N Syrigos, Mario Sznol, Roy S Herbst, Scott N Gettinger, Lieping Chen, David L Rimm, Programmed death ligand-1 expression in non-small cell lung cancer. Laboratory Investigation. ,vol. 94, pp. 107- 116 ,(2014) , 10.1038/LABINVEST.2013.130

B. Vogelstein, N. Papadopoulos, V. E. Velculescu, S. Zhou, L. A. Diaz, K. W. Kinzler, Cancer Genome Landscapes Science. ,vol. 339, pp. 1546- 1558 ,(2013) , 10.1126/SCIENCE.1235122