Genome evolution following host jumps in the Irish potato famine pathogen lineage

作者: Michael C. Zody , Sridhara G. Kunjeti , Nicole M. Donofrio , Blake C. Meyers , Chad Nusbaum

DOI: 10.1126/SCIENCE.1193070

关键词: Host adaptationEvolutionary biologyGenomic organizationGeneBiologyMolecular evolutionPhytophthora infestansEcologyGenomeLineage (genetic)Genome evolution

摘要: Many plant pathogens, including those in the lineage of the Irish potato famine organism Phytophthora infestans, evolve by host jumps followed by specialization. However, how host jumps affect genome evolution remains largely unknown. To determine the patterns of sequence variation in the P. infestans lineage, we resequenced six genomes of four sister species. This revealed uneven evolutionary rates across genomes with genes in repeat-rich regions showing higher rates of structural polymorphisms and positive selection. These loci …

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