CLINICAL AND HISTOLOGICAL EVALUATION OF LOW LEVEL LASER ON REGENERATION OF HIP JOINT CARTILAGE IN RABBIT
作者： H Joderi , P Mortazavi , Sharifi Davoud , I Sohrabi Hagh Doust , Abedi Gh.R.
DOI:
关键词: Orthopedic surgery 、 Low level laser therapy 、 Cartilage 、 Chondrocyte 、 Connective tissue 、 Xylazine 、 Surgery 、 Subluxation 、 Acepromazine 、 Medicine
摘要: Treating articular cartilage in dogs is a challenge the contemporary orthopedics of small animals. Currently application Low Level Laser being advocated for various disorders that why its effect evaluated experimentally induced defect hip joint. The experiment was conducted on 24 adult male rabbits which were divided into two groups (control & experimental) with 12 each. Effective anesthesia using combination acepromazine, ketamine and xylazine. After exposure subluxation right femoral head, maximum accessible denuded up to subchondral bone dental bit each rabbit. No treatment given control group, whereas experimental one subjected Therapy daily 1 minutes diode laser 630 nm 2 infrared 890 14 days daily, then further they subdivided 3 subgroup 4 duration ,2 months. There no trace firbrocartilage or formation group samples even end observation period .There remarkable connective tissue chondrocytes beneath located large lacunae having different type isogenic during month group.. Scattered collagen fibers between chondrocyte cells seen not enough fill period, drastic changes noticed three months full coverage area newly formed Davood Sharifi Department Clinical Sciences, Faculty Veterinary Medicine, University Tehran, Tehran-Iran e-mail: sharifid@yahoo.com
cabdirect.org参考文章(19)
Paul A. Dowdy, Anthony Miniaci, Steven P. Arnoczky, Peter J. Fowler, Derek R. Boughner, The effect of cast immobilization on meniscal healing. An experimental study in the dog. American Journal of Sports Medicine. ,vol. 23, pp. 721- 728 ,(1995) , 10.1177/036354659502300615
R. Lubart, H. Friedmann, A. Faraggi, S. Rochkind, TOWARDS A MECHANISM OF LOW ENERGY PHOTOTHERAPY LASER THERAPY. ,vol. 3, pp. 11- 13 ,(1991) , 10.5978/ISLSM.91-OR-01
J.Richard Steadman, Karen K. Briggs, Juan J. Rodrigo, Mininder S. Kocher, Thomas J. Gill, William G. Rodkey, Outcomes of Microfracture for Traumatic Chondral Defects of the Knee: Average 11-Year Follow-up Arthroscopy. ,vol. 19, pp. 477- 484 ,(2003) , 10.1053/JARS.2003.50112
Chung-Huang Chen, Huey-Shan Hung, Shan-hui Hsu, Low-energy laser irradiation increases endothelial cell proliferation, migration, and eNOS gene expression possibly via PI3K signal pathway. Lasers in Surgery and Medicine. ,vol. 40, pp. 46- 54 ,(2008) , 10.1002/LSM.20589
Dae Kyung Bae, Kyoung Ho Yoon, Sang Jun Song, Cartilage healing after microfracture in osteoarthritic knees. Arthroscopy. ,vol. 22, pp. 367- 374 ,(2006) , 10.1016/J.ARTHRO.2006.01.015
F. Özdemir, M. Birtane, S. Kokino, The clinical efficacy of low-power laser therapy on pain and function in cervical osteoarthritis. Clinical Rheumatology. ,vol. 20, pp. 181- 184 ,(2001) , 10.1007/S100670170061
Fred Behrens, Ellen L. Kraft, Theodore R. Oegema, Biochemical changes in articular cartilage after joint immobilization by casting or external fixation Journal of Orthopaedic Research. ,vol. 7, pp. 335- 343 ,(1989) , 10.1002/JOR.1100070305
S. L. PETERSEN, C. BOTES, A. OLIVIER, A. J. GUTHRIE, The effect of low level laser therapy (LLLT) on wound healing in horses Equine Veterinary Journal. ,vol. 31, pp. 228- 231 ,(1999) , 10.1111/J.2042-3306.1999.TB03177.X
K. A. Athanasiou, R. Fischer, G. G. Niederauer, W. Puhl, Effects of excimer laser on healing of articular cartilage in rabbits Journal of Orthopaedic Research. ,vol. 13, pp. 483- 494 ,(1995) , 10.1002/JOR.1100130403
Lee G Luna, Manual of histologic staining methods of the Armed forces institute of pathology Published in <b>1968</b> in New York NY) by McGraw-Hill. ,(1968)