Geomagnetic activity and enhanced mortality in rats with acute (epileptic) limbic lability

作者: Yves R. J. Bureau , M. A. Persinger

DOI: 10.1007/BF02726403

关键词: NocturnalPoison controlInternal medicineEndocrinologyMelatoninEpilepsyAmygdalaEarth's magnetic fieldMedicineHippocampusLimbic systemNeuroscience

摘要: Presumably unrelated behaviors (e.g. psychiatric admissions, seizures, heart failures) have been correlated with increased global geomagnetic activity. We suggested that all of these share a common source variance. They are evoked by transient, dopamine-mediated paroxysmal electrical patterns generated within the amygdala and hippocampus temporal lobes. Both probability propagation discharges to distal brain regions facilitated when nocturnal melatonin levels suppressed In support this hypothesis, present study demonstrated significant correlation Pearson r = 0.60 between mortality during critical 4-day period followed induction limbic seizures in rats ambient activity 3 4 days preceded death; risk 24 h indices exceeded 20 nT for more than 1 2 days.

参考文章(49)
Michael A. Persinger, The weather matrix and human behavior ,(1980)
Richard H. Lovely, Mary Ellen O'Connor, Electromagnetic fields and neurobehavioral function ,(1988)
George Paxinos, The Rat nervous system : Elsevier Academic Press,. ,(1985)
Michael A. Persinger, Katherine Makarec, Jean-Claude Bradley, Characteristics of limbic seizures evoked by peripheral injections of lithium and pilocarpine. Physiology & Behavior. ,vol. 44, pp. 27- 37 ,(1988) , 10.1016/0031-9384(88)90342-3
Donald P. Cain, Excitatory neurotransmitters in kindling: excitatory amino acid, cholinergic, and opiate mechanisms. Neuroscience & Biobehavioral Reviews. ,vol. 13, pp. 269- 276 ,(1989) , 10.1016/S0149-7634(89)80062-4
Alexander Lerchl, Russel J. Reiter, Kimberly A. Howes, Keico O. Nonaka, Karl-Arne Stokkan, Evidence that extremely low frequency Ca2+-cyclotron resonance depresses pineal melatonin synthesis in vitro Neuroscience Letters. ,vol. 124, pp. 213- 215 ,(1991) , 10.1016/0304-3940(91)90096-C
M. L. Zeise, P. Semm, Melatonin lowers excitability of guinea pig hippocampal neurons in vitro. Journal of Comparative Physiology A-neuroethology Sensory Neural and Behavioral Physiology. ,vol. 157, pp. 23- 29 ,(1985) , 10.1007/BF00611091
Paul B. Foley, Keith D. Cairncross, Andrew Foldes, Pineal indoles: Significance and measurement Neuroscience & Biobehavioral Reviews. ,vol. 10, pp. 273- 293 ,(1986) , 10.1016/0149-7634(86)90014-X