No Effect of Insecticide Treated Curtain Deployment on Aedes Infestation in a Cluster Randomized Trial in a Setting of Low Dengue Transmission in Guantanamo, Cuba

摘要: Objective & Methodology The current study evaluated the effectiveness and cost-effectiveness of Insecticide Treated Curtain (ITC) deployment for reducing dengue vector infestation levels in Cuban context with intensive routine control activities. A cluster randomized controlled trial took place Guantanamo city, east Cuba. Twelve neighborhoods (about 500 households each) were selected among ones highest Aedes previous two years, randomly allocated to intervention arms. Long lasting ITC (PermaNet) distributed clusters March 2009. Routine activities continued whole area. In both arms, we monitored monthly pre- post-intervention House Index (HI, number houses at least 1 container immature stages/100 inspected), during 12 18 months respectively. We effect on HI by fitting a generalized linear regression model negative binomial link function these data. Principal Findings At distribution, coverage (% using ≥1 ITC) reached 98.4%, median 3 distributed/household. After months, remained 97.4%. The local species was susceptible deltamethrin (mosquito mortality rate 99.7%) residual activity within acceptable 73.1%) after one year curtain use. Over month observation period adjusted ratio, versus clusters, 1.15 (95% CI 0.57 2.34). annualized cost per household implementation 3.8 USD, against 16.8 USD all ACP activities. Conclusion Deployment setting already actions does not lead reductions levels.