Genetic characterization of extraintestinal Escherichia coli isolates from chicken, cow and swine.

摘要: Phenotypic determination of antimicrobial resistance in bacteria is very important for diagnosis and treatment, but sometimes this procedure needs further genetic evaluation. Whole-genome sequencing plays a critical role deciphering advancing our understanding bacterial evolution, transmission, surveillance resistance. In study, whole-genome was performed on nineteen clinically extraintestinal Escherichia coli isolates from chicken, cows swine showing different susceptibility. A total 44 genes conferring to 11 classes antimicrobials were detected 15 19 E. (78.9%), 22 types plasmids 15/19 (78.9%) isolates. addition, these identified 111 potential virulence factors, 53 VFDB-annotated carried by all Twelve while the most frequent ones gad (glutamate decarboxylase), iss (increased serum survival) lpfA (long polar fimbriae). All harbored at least one genes. The findings comparative genomic analyses diverse study provided insights into molecular basis rising multi-drug coli.