High-Throughput Analysis of Gene Essentiality and Sporulation in Clostridium difficile

作者: Marcin Dembek , Lars Barquist , Christine J. Boinett , Amy K. Cain , Matthew Mayho

DOI: 10.1128/MBIO.02383-14

关键词: VirulenceBiologyGenetic testingBacterial geneticsHuman pathogenMicrobiologyMutagenesis (molecular biology technique)Computational biologyTransposon mutagenesisOrganismClostridium difficile

摘要: Clostridium difficile is the most common cause of antibiotic-associated intestinal infections and a significant cause of morbidity and mortality. Infection with C. difficile requires …

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